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These observations are in contrast to previous findings in the same Nrf2-GFP-HepG2 reporter model exposed to DEM or tert -butylhydroquinone, which indicate a lower Nrf2 response toward repeated treatments (Bischoff et al
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Mice null for ALDH1A1 and ALDH2 exhibit Parkinson's disease-like age-dependent deficits in motor performance and significant increase in biogenic aldehydes
