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This finding is supported by another proton magnetic resonance spectroscopy trial involving the dorsal anterior cingulate cortex, where glutamate levels were significantly higher in cocaine-dependent patients compared with healthy controls [16]

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Our results in nicotine CPP are consistent with an earlier work that showed L-theanine reduced nicotine conditioned reward in the CPP test in mice (Di et al., 2012)

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The tail was then gently pulled until the mouse released its grip

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