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A dual-luciferase reporter assay kit (Promega, E1910) was used to measure the luciferase activity
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A similar protection against steatosis has been previously noted in GCLM KO mice challenged with other liver toxicants 38 or stress-inducing diets 17,39
These include the production of nitric oxide, accelerated lipid oxidation, and depletion of glutathione, all of which lead to severe oxidative stress [23]
