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Notably, prophylactic administration of curcumin prior to amyloid- deposition demonstrates preventive potential for Alzheimer's disease, possibly through facilitating amyloid-42 clearance from the brain to peripheral circulation (Mei et al., 2020)
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Thus it can be seen as arginine plays a crucial role in stability and flexibility of protein, as this types of interaction can be elucidated by opposite charge attraction, length and flexibility of side chain, and the potential to produce excellent hydrogen-bonding geometries with other biomolecules like nucleobases and phosphate groups
