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EVs containing integrin beta-like 1 (ITGBL1) activate fibroblasts in distant organs by inducing the production of pro-inflammatory cytokines such as IL-8 and IL-6, ultimately promoting the growth of metastatic tumor cells (Ji et al., 2020)
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Severe glutathione synthetase deficiency Patients have symptoms as in moderate glutathione synthetase deficiency and, in addition, they develop progressive neurological symptoms, e.g
