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This maintenance of m and mPTP closure prevents mitochondrial swelling, calcium overload, and cytochrome c release, all of which are crucial to delaying or inhibiting apoptosis, particularly in neurodegenerative conditions [60]

Mental Health Recent studies suggest that NAC may improve mental health conditions by regulating glutamate levels in the brain

The reason for this unexpected observation was that paralysis of an essential cellular defense mechanism like autophagy leads to faster accumulation of cellular waste, which triggers an enhanced rate of cell turnover through apoptosis and compensated enhanced regeneration [151]

In: Current Diagnosis & Treatment: Emergency Medicine 7e
