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Its identification as the first selenoenzyme, and the current understanding of its enzymology are discussed in a separate article in this issue (Floh et al., special issue)

Nature (2010) 467(7317):8328.10.1038/nature09410 280 AhlgrenMMelbyeMWohlfahrtJSorensenTIA

1 Introduction As societys emphasis on health and the pursuit of an improved quality of life steadily intensifies, there is a growing interest in the scientific exploration of strategies to augment athletic performance and physical adaptability

Chemotherapy drug Lobaplatin triggers pyroptosis in cervical cancer and colorectal cancer by activating GSDME (Chen et al., 2022)
