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3 RGN-259 Phase 3 Trial in Neurotrophic Keratopathy Sosne et al., International Journal of Molecular Sciences (2022) This Phase 3 randomized, placebo-controlled, double-masked clinical trial evaluated topical 0.1% RGN-259 (full-length recombinant T4 ophthalmic solution) in patients with neurotrophic keratopathy
The protective effects of the administration of antioxidant NAC on a murine asthma model was demonstrated in two studies

(ii) Triggered as realized through acid activation
Epidermal growth factor differentially augments G i -mediated stimulation of c-Jun N-terminal kinase activity Br J Pharmacol 142: 635646, [PubMed] DOI: Watanabe, G, Lee, RJ, Albanese, C, Rainey, WE, Batlle, D and Pestell, RG (1996)