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In addition, BHB induces lysine -hydroxybutyrylation, a histone modification that regulates genes involved in redox homeostasis and energy metabolism [47]
[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Weiss N, Papatheodorou L, Morihara N, Hilge R, Ide N
The acetaldehyde produced by the ADH reaction, as well as the ROS produced via CYP2E1 oxidation, both can interact with proteins and other biomolecules in the cell to form both stable and unstable adducts
10.1016/S0140-6736(17)32873-8 227 ZazuetaC.Reyes-VivasH.ZafraG.SnchezC
