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Description
Biochemical reports also demonstrated that enhanced oxidative stress, dysregulated apoptosis, and extensive inflammatory reactions mediated by overexpressed inflammatory factors [such as tumor necrosis factor (TNF-), interleukin 1 (IL-1), and interleukin 6 (IL-6)] were served as the underlying mechanisms for the occurrence of various CSD-relevant diseases (810)

The involvement of glutamatergic pathways in the pathophysiology of addiction was also confirmed

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