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Structural deterioration is characterized by depletion of goblet cells and disruption of the mucus layer
Briefly, glutathione disulfide is held in the proximity of the catalytically active reducing thiol group and one thiol glutathione unit is detached in the first of the two reductive steps, leaving the enzyme in a cysteine-glutathionylated form

These functions make NAC supplementation a viable therapeutic option for various health issues

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