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Although these therapies have shown considerable effectiveness in clinical studies, researchers have raised concerns regarding the loss of lean tissue, which has emerged as a significant clinical issue
The treatment group received standard physical rehabilitation combined with 500 mg of Acetyl-L-Carnitine daily, while the control group received rehabilitation alone
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Preliminary CRISPR screening and functional studies revealed that inactivation of the WRC can promote actin polymerization, regulate actin cytoskeletal dynamics, and inhibit disulfidptosis (Liu et al., 2023a)
