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After binding with PERK, TMAO selectively activates PERK-mediated UPR, thereby promoting metabolic dysfunction ( Of note, TMAO in the pathogenesis of Alzheimers disease (AD) indicated that PERK is not the only mechanism by which TMAO induces UPR

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Menschen mit chronischen Herzkrankheiten (auch Arteriosklerose) sein, denn L-Carnitin frdert die Sauerstoff- und Nhrstoffversorgung des Herzens und verringert so das Risiko der typischen Folgeerkrankungen (Herzinsuffizienz, Angina Pectoris, Herzinfarkt)