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doi: 10.1007/s00018-024-05532-5

Because glutamate signalling is ubiquitous in the brain (and concentrated in other tissues such as the heart, adrenal glands and the gastrointestinal tract Julio-Pieper et al 2011) this neuroinflammatory cycle can result in a wide range of symptoms that then result in a variety of differential diagnoses

H., Lopipero, P

Mitochondrial and cytoplasmic ROS have opposing effects on lifespan
