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Description
It is an l-histidine derivative that is N ,N ,N -trimethyl-l-histidine in which the hydrogen at position 2 on the imidazole ring is replaced by a mercapto group

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Administration of Klotho decreased phosphorylation of FOXO3 ( p = 0.0355), and enhanced activity of glutathione peroxidase ( p = 0.0452) and superoxide dismutase ( p = 0.0060) in IRI + Klotho group
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