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174,175,176 In the UC animal model, the more severe the colon injury was, the lower the abundance of Akkermansia

[DOI] [PubMed] [Google Scholar] 43.Ronnov-Jessen L., Petersen O.W

Aif3 splicing variant elicits mitochondrial malfunction via the concurrent dysregulation of electron transport chain and glutathione-redox homeostasis
In cancer, these break normal physiological bias, shattering signaling guardrails, leading to dedifferentiation (Nussinov, Reference Nussinov2025)
