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[9] CoQ10 is a fat-soluble, vitamin-like coenzyme found naturally in every cell, with especially high levels in energy-intensive organs like the heart, liver, and kidneys

Advances in metabolomics and nutrigenomics suggest that specific patient subpopulations may realize the greatest benefit, indicating a move away from generalized supplementation toward a more targeted adjunctive therapy integrated with evidence-based cardiovascular care (Figure 1), distinguishing well-established clinical evidence from hypothesis-generating findings, and highlights emergent areas where nutraceuticals may reshape preventive and therapeutic cardiology

Spiewak, M

1 Calculated as 24-h TMAO minus baseline TMAO