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NAPAs are highly uniform MALDI platforms with broad molecular coverage, ultra-trace sensitivity, and tissue imaging capabilities in MALDI-MS

PMID: 32960936 Int Immunopharmacol Colistin-induced acute kidney injury via zinc Dyshomeostasis-triggered GSDMD-executed Pyroptosis

The concept is elegant, but larger human trials as an anti-obesity treatment were disappointing

The main limitation of this study was the lack of consideration of factors that could influence the rate of penetration, such as the anatomical site of application, temperature, humidity, the nature of the vehicle, and the presence or absence of disease