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doi: 10.1007/s40263-014-0214-y
Although the tissue distribution of CD38 has been widely studied and described, its functions remain only partially understood

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A preliminary study evaluating diabetic peripheral neuropathy has demonstrated that targeted supplementation with these active B-vitamins (along with pyridoxal 5'-phosphate) can actually increase epidermal nerve fiber density, meaning the nerves physically begin to regrow and heal, leading to a reduction in pain and paresthesia
