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A New Embedded Process for Compartmentalized Cell-Free Protein Expression and on-Line Detection in Microfluidic Devices

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Exhausted T cells show a reduced capacity to perform metabolic processes such as aerobic glycolysis and oxidative phosphorylation (OXPHOS), both due to external influences and intrinsic signals, such as PD-1 expression (136)

In summary, these findings demonstrate that GPR146 regulates adipose function in a stage-specific manner-promoting adipogenesis via Gq-PKC-AKT signaling during differentiation and stimulating lipolysis via ERK signaling in mature adipocytes-highlighting the context-dependent nature of GPR146-mediated metabolic control