glutathione conjugation steps General scheme of (GSH) to a generic Design principle of the feedback
Description
From 7 to 14 are bases with 14 being the 0 to 14

PML is a ROS sensor activating p53 upon oxidative stress

Cell Commun Signal 21 , 269 (2023)

Mitochondrial oxidative phosphorylation, essential for neuronal energy production, also generates reactive oxygen species (ROS), which increase with age and contribute to oxidative stress
