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These adverse effects, including peripheral neuropathy and hearing loss, can have a profound impact on patient quality of life and require careful monitoring throughout treatment [44, 45]

Mitochondrial Uncoupling Mitochondria serve as the principal sites of cellular energy production, generating adenosine triphosphate (ATP) via oxidative phosphorylation

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Therefore, under laser irradiation, the local temperature around inorganic matrices, especially NMs, can become extremely high, sufficient to desorb most analytes