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Description
The distinction is in the research target

Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, et al

Despite the widespread use of levothyroxine replacement therapy, a substantial proportion of patients continue to experience persistent symptoms and metabolic dysregulation even after achieving biochemical euthyroidism

Among these alleles, 4 were obtained from lines collected before the use of DDT and so it is unlikely that the G171K change occurred in response to DDT selection
