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Description
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Validating a large animal literature [e.g., (98)], newer human studies have demonstrated that exogenous proinflammatory cytokines (e.g., injected IFN-) or other immune challenges (e.g., injected typhoid vaccine) can influence behavior and fMRI brain activity in otherwise healthy humans [e.g., (99102)]

Gastroenterology 84 ShibataT.OhtaT.TongK

Methods An alternative therapeutic strategy centers on genetically guided pro-dopamine regulation, which aims to transmodulate dopaminergic signaling to mitigate hyperalgesia
