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Pollard & Pomfrett claim that a dose of DSIP given during the course of the day will promote improved sleep on the next night and for several nights thereafter,4 so the dose frequency here could be an example of less frequent administration

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These results clarify diverse oscillatory mechanisms in PD symptom improvement, emphasizing aberrant oscillations' crucial role in tremor and rigiditybradykinesia pathophysiology
10.1021/acs.chemrev.1c00484
