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44 An open-label, uncontrolled trial in 51 patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) found improvements in 34 patients after 3 months of supplementation with hydroxo-B12, 10 000 mcg twice per week as nasal drops

Cell (2011) 144(5):64674

Wang S, Wang Y, Wan X, Guo J, Zhang Y, Tian M, et al

You can also find vitamin B12 in fortified cereals and nutritional yeast products