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The molecular mechanisms underlying neuronal death include chronic inflammatory response and OS (Gaki and Papavassiliou, 2014, Stojkovska et al., 2015), which is characterised by the presence of microglial cell activation, reactive astrogliosis (Marino et al., 2020)

& Itami, S

Effective prophylactic and therapeutic treatments are urgent for this group of seemingly inexorable diseases

IUBMB Life 60:232235 Srivastava PC, Robins RK (1983) Synthesis and antitumor activity of 2-beta-d-ribofuranosylselenazole-4-carboxamide and related derivatives
