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Many genetic variations in G6PD have been reported in various ethnic populations and accountable for deficiency/decreased activity of enzyme

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(102) found that 2-month-old male Wistar rats subjected to 6 months of EODF exhibited reduced acetylcholine transferase (ChAT) reduction in the frontalparietal cortex after basal forebrain injection of amygdalin compared to the AL group, suggesting that EODF may exert partial neuroprotective effects against this damage

Notably, previous meta-analyses have been inconsistent, and no further meta-analyses have been published in the last 5 years