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Description
It can be caused by viral or bacterial infections, or by immune cells mistakenly attacking the brain
10.1097/WNR.0b013e32832fbf14 20
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More recently, the same residue was mutated back to a non-acidic residue uniquely in legume plants, which resulted in prephenate-specific TyrA p enzymes (Schenck et al., p were converted into microbial TyrA a and then to legume-specific TyrA p by altering the same active site residue from a non-acidic to an acidic, and then back to a non-acidic residue
