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As noted by Kraus et al., Nature Medicine , NNMT inhibition in white adipose tissue significantly increased energy expenditure and reduced fat mass in animal models without changes to diet or activity

Can An Uncontested Disposed Case Be Reopened

Zheng, M., slund, F

Taken together, these findings indicate a potential oncogenic role of FASN and a potential high therapeutic index due to the lack of essentiality in most normal tissues