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The same was observed in clinical CD patients and in trinitrobenzene sulfonic acid (TNBS)-induced experimental colitis: increased expression of ACSL4/MDA/PTGS2/iron and inhibition of GPX4, which was ameliorated by treatment with Ferr-1 (63)

However, bioinformatic analyses of the RNA-Seq profiles of the naive and GC B cells used in that workwhich involved transfers of anti-NP BCR knock-in cells into a nonphysiological recipient settingsuggested that these cells differed from those in a less-engineered polyclonal setting and response [186]

Relatively higher concentrations of AZD3965 were used to inhibit cancer cells

In recent years, research on ferroptosis in the field of ophthalmology has gradually emerged, and a large amount of evidence has shown that it is closely related to the occurrence and development of ophthalmic diseases such as age-related macular degeneration (AMD), diabetic retinopathy (DR), retinal ischemiareperfusion injury (RIRI), retinitis pigmentosa, dry eye disease, cataracts, and glaucoma