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The current review highlights recent research findings on the modulation of GSH, its redox couple (reduced glutathione/oxidised glutathione), and other GSH-related enzymes (GR, glutathione peroxidase, GST) involved in the detoxification of harmful ROS and their reaction products in toxic metals and metalloids-exposed fish.

In this study, we have developed the method of the effective conversion of GSH to -EC to achieve the optimal reaction conditions for repeated batch production and potential application in industrial -EC production using the phytochelatin synthase-like enzyme NsPCS