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Sources for obtaining these marker genes and methods for their use are provided in Sambrook and Russel (2001) "Molecular Cloning: A Laboratory Manual (3rd edition), Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory Press, New York

Lovell MA, Ehmann WD, Butler SM, Markesbery WR

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The NFB pathway is initiated by the degradation of IB, enabling NF-B to translocate to the nucleus and promote the transcription of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which further damage endothelial cells and disrupt tight junction proteins (Figure 3) [188,189,190]