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Description
FIGURE 5 Recent crystallographic studies on L-Glu-bound BlGGT demonstrated that its active site channel constitutes two extensive pockets at the intersubunit interface lined mainly by hydrophobic residues
Reduced intracellular glutathione levels or increased iron concentrations further exacerbate these pathologic phenotypes

Multifunctional: Studied in sleep regulation, hormone modulation, and stress response

Global profiling of AMG510 modified proteins identified tumor suppressor KEAP1 as an off-target