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ox-LDL is not recognized by the LDL receptor and is subsequently taken up by scavenger receptors in macrophages to form foam cells and so lead to atherosclerotic plaques (Boullier et al., and H 2 O 2 stimulate stress-related signaling mechanisms such as NF-B, p38-mitogen activated protein kinases (p38-MAPK) and signal transducers and activators of transcription-Janus kinases (STAT-JAK), resulting in vascular smooth muscle cell migration and proliferation

First, IFN or TNF- induced the STAT1/IRF-1 signaling pathway

Morning and/or evening on cleansed skin