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Description
Specifically, LDHB depletion impairs GSH synthesis and leads to hypersensitivity of KRAS -mutant cancer cells to ferroptosis inducers, which is causally linked to increased glutaminolysis and mitochondrial ROS
Resveratrol upregulates miR-455-5p to antagonize cisplatin ototoxicity via modulating the PTEN-PI3K-AKT axis
DIM (diindolylmethane) is a natural organic compound that promotes healthy estrogen metabolism
However, studies have proposed NO to represent a double-edged sword with its overproduction leading to a multitude of NO by-products implicated in mutational events and carcinogenesis
