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A study has confirmed that the expression of glycolysis-related genes in tumor samples from patients with melanoma and non-small-cell lung cancer is negatively correlated with T cell infiltration, and that tumor glycolysis is related to the efficacy of adoptive T cell therapy (ACT), suggesting that the glycolytic pathway may be a candidate target for combined therapeutic intervention (283)

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Alpha and Mu classes of GST2 superfamily enzymes, able to protect the cell from toxic endogenous or xenobiotic compounds, are abundantly expressed in rat liver, where they represent 43% and 56%, respectively, of the entire pool of cytosolic GSTs [54]

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