l carnitina contra indicação L-carnitina: o que é, para que serve (e como tomar) Acetil L-carnitina 500mg + Ácido

Mammalian target of rapamycin (mTOR), along with other proteins and intracellular signaling pathways such as PPAR-gamma coactivator 1-alpha (PGC-1), sirtuins, nuclear respiratory factor 1 (NRF1), AMPK, mitochondrial transcription factor A (TFAM), and PTEN-induced kinase 1(PINK)/E3 ubiquitin ligase (PARKIN) are involved in the mitochondrial quality control, which in turn depends on the coordination between mitochondrial biogenesis, mitochondrial dynamism, and mitophagy (Vives-Bauza et al., 2010

Factors such as ageing, stress, poor nutrition, and exposure to environmental toxins can all contribute to this reduction

In addition to the role mentioned above in the process of oxidative stress, the GPX family also plays a unique role in tumor development (Laribi et al., 2021), viral infection (Strycharz-Dudziak et al., 2020), obesity (Gusti et al., 2021), apoptosis (Rusetskaya et al., 2019), signal transduction, and inflammation (Rusetskaya et al., 2019)

Arch Biochem Biophys (2011) 515:4653