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Description
The role of pharmacoepigenomics
Table S1 Subject demographics and clinical details
There, HIF- subunits dimerize with aryl hydrocarbon receptor nuclear translocator, recruit transcriptional coactivators such as p300/CBP, and bind to hypoxia-responsive elements in target genes to activate transcription
Ibrutinib is mainly metabolized to dihydrodiol-ibrutinib (DHI) by CYP3A4 and to a lesser extent by CYP2D6 [6]
