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CAT, a crucial enzymatic system able to inactivate ROS and their by-products, did not return to normal levels after a short period of abstinence

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The proposed mechanism involves controlling glutamate release in the synaptic cleft, modulating NMDA receptor stimulation, affecting excitatory amino acid transporter (EAAT)-mediated reuptake, and maintaining the glutamate/glutamine cycle within astrocytes

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