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Description
Unfortunately, the progress in deciphering the molecular processes underlying leptin and ghrelin resistance in obesity has not yet translated into novel and effective obesity treatments, which highlights the need for better understanding of the mechanisms of obesity-associated leptin and ghrelin resistance
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In addition, the other mechanisms have been reported to stabilize NRF2 through interfering with the formation of the NRF2-KEAP1 complex
10.1021/cb700233t
