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Consistently, stress-induced depression models exhibit decreased prefrontal Bcl-2 protein levels and increased caspase-3/Bax expression, which can be reversed by the antidepressant venlafaxine [83]

DOI: Published online: August 29, 2022 1 Divison of Endocrinology & Metabolism, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea 2 Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea 3 Divison of Endocrinology & Metabolism, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Corresponding author: Sung Hee Choi

Consequently, ApoC-III influences atherosclerosis by promoting LDL retention and aggregation in the subendothelial space, as well as triggering inflammatory cascades and smooth muscle cell proliferation in the arterial wall 39

Without adequate choline, the liver cannot package triglycerides into lipoproteins for export