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Description
Several adverse biotic and abiotic environmental factors can lead to endoplasmic reticulum (ER) stress as the capacity of the protein folding and ER-associated degradation (ERAD) machinery is exceeded
38 Le CorreM.NoristaniH
& Simionescu, A.) 107130 (Tech Open Access Publisher, 2011)
Lead accumulation in tissues promotes oxidative DNA damage, and causes anemia, in part through inhibition of the activity of -aminolevulinic acid dehydratase, an enzyme involved in the biosynthesis of heme [17, 24]
