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Some people book: One injection every few months (as a top-up) A monthly session during busy or stressful periods A weekly course when recovering from deficiency or burnout I always start with a quick consultation, so we can decide whats best for you

Patients often report better symptom control when injections are given every 57 days SubQ rather than every 14 days IM

So injecting beyond a certain point may cause your cells to fight off the excess B12 so hard that it might reduce the amount of active cellular B12 - probably not to dangerous levels, but possibly sufficient to trigger some symptoms

Furthermore, the number of T cells (CD3), B cells (CD19) and macrophages (CD68) was increased in the lamina propria of new-onset treatment-nave RA patients (Fig