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Analysis of PolyQ aggregation Thirty animals containing PolyQ repeat length polymorphisms, AM140 ( rmIs132 [P unc-54 ::Q35::YFP]) and AM141 ( rmIs133 [P unc-54 ::Q40::YFP]), were scored for the actual number of YFP puncta aggregates present throughout the animal

Due to strong influences of reproductive cycles on physiological responses of female rats all experiments were performed on male subjects only

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The mechanism research has generally focused on the capacity of MLE to activate antioxidant systems typically via the activation of nuclear factor erythroid 2-related factor 2 (Nrf2) to prevent ROS-induced cellular damage (Reference Mundkar, Bijalwan and Sone1,Reference Calabrese and Kozumbo13)