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Description
Several hypotheses have been postulated to explain how these amylin aggregates can cause -cell loss due to their toxic effects [27]

PMID: 9717825

[DOI] [PubMed] [Google Scholar] 65.Dobs AS, Meikle AW, Arver S, Sanders SW, Caramelli KE, Mazer NA

However, morphological studies have demonstrated that cochlear development proceeds normally, and the gross morphology of the organ of Corti is normal, indicating that Lgr5 is dispensable for hair cell formation (Chai et al., Lgr5 -positive cells in the postmitotic neonatal cochlea that have garnered attention recently as a possible source of hair cell progenitors
