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Appropriate candidates for the stack include post-surgical patients, those with severe or multiple injuries, athletes needing rapid return to competition, and individuals who tried BPC-157 alone with partial response

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Berberine reduced the production of inflammatory cytokines such as IL-1 , IL-6, and TNF- , increased the anti-inflammatory cytokine IL-10 and increased the ratio of M1 and M2 macrophages to levels seen in healthy rodents