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This is the mechanistic reason the ladder is deliberately patient rather than arbitrarily cautious

Figure 4 5.10 Summary of ferroptosis-targeted therapeutic strategies Based on the disease-specific discussions above, ferroptosis-targeted therapeutic strategies can be categorized into three main approaches based on their mechanisms of action: Iron Chelators (e.g., Deferoxamine, Deferiprone) sequester labile iron to limit Fenton chemistry-driven hydroxyl radical generation

From this perspective, probiotics, prebiotics, and postbiotics constitute the most important microbiota-mediated approaches in balancing inflammation and supporting the healing process following injury (52)

Pan Y, Zhang H, Li M, He T, Guo S, Zhu L, Tan J, Wang B