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This expression induces neurodegeneration in a time-dependent manner and is modulated by factors, which promote proper proteostasis
Next, we packaged the shRNA into adenovirus and delivered it into the back of plucked mice by subcutaneous injection
In hepatocytes, the key factors that regulate cysteine availability include membrane transport of cysteine (via the ASC system), cystine (via the X c - system which is induced under oxidative stress), methionine (via the L system) and the activity of the transsulfuration pathway [47,52,53]
doi: 10.1038/351122a0
