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Description
show that amlodipine may increase flow-mediated dilation, NO, and eNOS activity in human umbilical vein endothelial cells through decreased PKC phosphorylation, and reduced PKC-dependent threonine 495 phosphorylation on eNOS (144)

While this has been positive in raising the products profile, it has also prompted many to look at its safety in their clinic

Iwatsubo, T

2016 Dec 20;12(12):e1006486
